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Mechanism of Action

A Mechanism of Action That Is Unique to SAPHNELO*

Adapted from SAPHNELO Product Monograph¹*

Approximately 60-80% of adult patients with SLE express elevated levels of type I IFN inducible genes, which are associated with increased disease activity and severity.¹*

IFN-1=interferon type I; SLE=systemic lupus erythematosus.

* Clinical significance has not been established.

Mechanism of Action

A Mechanism of Action That Is Unique to SAPHNELO*

Approximately 60-80% of adult patients with SLE express elevated levels of type I IFN inducible genes, which are associated with increased disease activity and severity.1*

Approximately 60-80% of adult patients with SLE express elevated levels of type I IFN inducible genes, which are associated with increased disease activity and severity.¹*